interferon alpha drug

Interferon alpha-2b is an anti-viral drug originally approved as an injection in the mid-1980s (Intron A, Schering Corporation).It is currently approved for indications including melanoma, hepatitis C, and ano-genital warts (AGW)—a condition caused by human papilloma virus ( HPV). Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Roferon-A (Interferon Alfa-2A) It is also used to treat certain types of cancer. Multum no se responsabiliza por ningún aspecto del cuidado médico que reciba con la ayuda de la información que proviene de Multum. Changes are usually mild, but rarely they can be more severe. For example, in January 2001, the Food and Drug Administration (FDA) approved the use of PEGylated interferon-alpha in the USA; in this formulation, PEGylated interferon-alpha-2b (Pegintron), polyethylene glycol is linked to the interferon molecule to make the interferon last longer in the body. Generic Name: interferon alfa-2aBrand Name: Roferon-A. red, warm and itchy bumps on the skin (like nettle rash), breathlessness, wheezing, a cough or sudden difficulty with breathing. Interferon alpha is taken by injection and it has some side effects so it is not the first choice of therapy for most people with MPNs. Wearing natural fabrics such as cotton may help. It might be an old link or maybe it moved. Interferón alfa-2b funciona para tratar el virus de la hepatitis C (HCV) y el virus de la hepatitis B (HBV) al disminuir la cantidad del virus en el cuerpo. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The interferons may neutralize these foreign bodies, but in some cases, the cat will need additional supplementation of interferon. Algunas marcas de interferon alfa-2a son intercambiables mientras que otras no lo son. Schaefer M(1), Mauss S. Author information: (1)Department of Psychiatry and Psychotherapy, Kliniken Essen-Mitte, Ev. El interferon alfa-2a es una proteína. Interferon alfa-2b también se usa para el tratamiento de la hepatitis B o C crónica en los adultos y para tratar la hepatitis B crónica en los niños de al menos 1 año de edad. This was compared to people who took a placebo, a dummy treatment with no drug in it. 15 Because peginterferon alfa-2b is still being studied in people with HIV, information on possible side effects of the drug is not complete. ¿QUÉ ES EL INTERFERÓN? Interferon is a type of immunotherapy drug called an immune system modulator. Patients receiving interferon alfa may be switched to peginterferon alfa. It is best to read this information with our general information about the type of cancer you have. Once-weekly peginterferon alfa-2a treatment for 4 weeks in healthy subjects was associated with a 25% increase in theophylline AUC; If coadministered, monitor theophylline serum levels and consider appropriate dose adjustments ; NRTIs The long history of elevated interferon (IFN)-alpha in association with disease activity in patients who have systemic lupus erythematosus (SLE) has assumed high significance in the past decade, with accumulating data strongly supporting broad activation of the type I IFN pathway in cells of patients who have lupus, and association of IFN pathway activation with significant clinical manifestations of SLE … Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Try to pace yourself and plan your day so you have time to rest. This can be reduced by having the injections in different places. El interferon alfa-2a se aplica únicamente mediante una inyección intramuscular o subcutánea. Give them the contact details for your cancer doctor so they can ask for advice. Antes de usar interferon alfa-2a, dígale a su médico si usted. El interferon alfa-2a puede causar somnolencia, mareo o deteriorar su agudeza mental. Your nurse can give you more advice. This is who we mean when we mention doctor, nurse or pharmacist in this information. La información sobre el medicamento incluida aquí puede tener nuevas recomendaciones. Alternative name(s): Interferon alpha-A. Hable con su médico acerca de cualquier efecto secundario que le parezca inusual o que le cause molestia. They can give you treatments to help. Si el interferon alfa-2a que usted usa no tiene preservativos, use únicamente una dosis de cada botellita. Roferon-A (interferon alfa-2a, recombinant) is indicated for the treatment of chronic hepatitis C and hairy cell leukemia in patients 18 years of age or older. Interferons-alpha (IFN-alpha) are pleiotropic cytokines belonging to type I IFNs, extensively used in the treatment of patients with some types of cancer and viral disease. El Interferón alfa-2a se encuentra en una clase de medicamentos llamados interferones. Beba de 6 a 8 vasos de agua diariamente para asegurar estar bien hidratado, en especial al inicio de la terapia. Copyright 1996-2012 Cerner Multum, Inc. All categories. tiny red or purple spots on the skin that may look like a rash. You will have regular blood tests during your treatment. Contact the hospital straight away on the 24-hour contact number you have if: It is important to follow any specific advice your cancer treatment team gives you. You may get these symptoms soon after you start treatment. Interferon Alpha- Two B(Pegintron) generic is an antiviral drug, prescribed for chronic hepatitis B and C either alone or with other medications. Some medicines can affect this treatment or be harmful when you are having it. Cancer 1994; 74: 958-61. Comuniquese con su médico de inmediato si siente dificultad al respirar, dolor de pecho, vista borrosa, o perdida de la vista. Peginterferon alfa-2a (brand name: Pegasys) is a drug that has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis B virus infection and chronic hepatitis C virus infection. DisGeNET i: 3440: PharmGKB i: PA29662: Miscellaneous databases Pharos i: P01563, Tbio: Protein family/group databases. If your immune system is weak, you need to avoid live vaccinations such as shingles. This includes: Some people may need a drip to give them extra platelets. Rarely, this treatment can cause complete hair loss. As a prime example, interferon alpha (IFNα) is an important protein drug for the treatments of a wide range of viral and cancerous diseases mainly through its immunostimulatory functions [18,19], but it is unstable with a short circulation half-life [, , , , ]. The drugs may harm a developing baby. We’re here to provide physical, financial and emotional support. IFN-alpha can affect tumor cell functions by multiple mechanisms. Interferon-alpha (or interferon-alfa ... Interferons can harm an unborn baby. Types of interferon alpha. Tampoco se sabe si alfa interferons curará la hepatitis o evitará la cirrosis, insuficiencia hepática, o cáncer del hígado que puede ser consecuencia de una infección con el virus de la hepatitis. This treatment can reduce the number of platelets in your blood. Llame a su médico o busque atención médica de emergencia si se siente deprimido o está pensando en el suicidio; se siente más irritable de lo normal, ansioso (nervioso), o agresivo; o nota otros cambios del humor o comportamiento. Interferon suppresses the production of blood cells via multiple and complex mechanisms which is why it can be useful in patients with various types of MPN with overactive bone marrows. Interferon is usually given as an injection under the skin (subcutaneously). If you have blurred vision, feel drowsy, tired, or have difficulty concentrating, do not drive or use machines. In 13 patients with metastatic renal cell carcinoma, the combination of However, heightened levels of serum interferon alpha and expression of interferon response genes are common in lupus patients. Sometimes your doctor will stop the interferon. This is usually mild and goes back to normal after treatment. Interferon alpha. m.schaefer@kliniken-essen-mitte.de Interferon alpha is a drug that may be used in cats to manage conditions such as the FeLV, infectious peritonitis or FVH. Whatever cancer throws your way, we’re right there with you. Comuniquese con su médico de inmediato si contrae fiebre, síntomas de una infección, o sangramiento inusual o contusiones. Los interferones se liberan en el cuerpo como respuesta a las infecciones virales. Interferon may make you sweat more. People with weak immune systems can have this type of vaccination. Your doctor will talk to you about how to manage this. FDA label information for this drug is available at DailyMed. Sin embargo, si ya es casi la hora de aplicar la próxima dosis, espere y use únicamente la siguiente dosis normal. For example, in January 2001, the Food and Drug Administration (FDA) approved the use of PEGylated interferon-alpha in the USA; in this formulation, PEGylated interferon-alpha-2b (Pegintron), polyethylene glycol is linked to the interferon molecule to make the interferon last longer in the body. What's going on near you? Save these numbers in your phone or keep them somewhere safe. Your doctor or nurse may talk to you about vaccinations. Interferon is made by a variety of drug companies and is known under several brand names according to the manufacturer. The company is also working with the USFDA to start an Investigational New Drug (IND) application for Pegylated Interferon alpha-2b in order to initiate clinical trials in US If you have headaches more often or they are more severe than usual, tell your doctor or nurse. Since the arrival of coronavirus (SARS-CoV-2) in Nicaragua, the Ortega government has lauded the version of this drug produced in Cuba as a panacea. There are some important things to remember about interferon: We explain the most common side effects of this treatment here. Éstos son muy comunes al inicio de la terapia y pueden disminuir con el uso continuo. This medication is classified as a "cytokine." If your blood cell levels get too low your doctor may stop your treatment for a short time until this improves. This drug is mainly used for treating melanoma ( 9 ), leukemias and lymphomas ( 10 , 11 , 12 ), and infections by hepatitis B virus and hepatitis C virus ( 13 , 14 ), IFN-alpha-2b, as well as all other interferons, are in a class of proteins called cytokines. In addition, it is indicated for chronic phase, Philadelphia chromosome (Ph) positive chronic myelogenous leukemia patients who are minimally pretreated (within 1 year of diagnosis). 1. La información de Multum sobre drogas no sanciona drogas, ni diagnóstica al paciente o recomienda terapia. +33 (0)3 90 20 54 70 El interferón alfa-2b (conjugado de PEG) es un fármaco clasificado en la categoría C (su utilización durante el embarazo se recomienda únicamente si el beneficio para la madre supera el riesgo al feto). Your doctor can give you anti-sickness drugs to help prevent or control sickness. 3 It is also being studied as an investigational drug to treat HIV infection. Drug Approvals by the Medicines Control Council in South Africa containing Interferon alpha-2b, Recombinant. These symptoms can be quite severe at the start of your treatment with interferon. These may be done before, during, and sometimes after treatment. Jacobsen MB, Hanssen LE, Kolmannskog J, et al. Los interferones se liberan en el cuerpo como respuesta a las infecciones virales. Hable con su médico y farmacéutico antes de tomar cualquier medicina, ya sea recetada o no, incluyendo los productos herbarios. Interferon may be given on its own or in combination with other cancer drugs. Revision Date: 3/21/03 1:13:26 PM. El interferon alfa-2a se usa para tratar la hepatitis C crónica, la leucemia de células pilosas, el sarcoma de Kaposi relacionado con el SIDA y algunos tipos de leucemia mielógena crónica (CML). Sucking sugar-free sweets may help with this. Find patient medical information for Interferon Alfa-2B Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. If you have any problems with your mouth, tell your nurse or doctor. This treatment can affect your appetite. These can be signs of infection. Rarely, some people have an allergic reaction to interferon. Generic drug Interferon Alpha-2B available with manufacturer details. Your cancer doctor or GP can tell you more about live vaccinations. Store it in the fridge and follow any instructions given by your pharmacist. It also may not prevent the spread of hepatiti… © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Las drogas que no sean las señaladas aquí pueden también tener interacciones con el interferon alfa-2a. Si usted tiene alguna pregunta acerca de las drogas que está tomando, consulte con su médico, enfermera, o farmacéutico. In some people, interferon can affect their kidneys or liver. What This Drug Is Used For: This medication is used to treat chronic hepatitis C. This medication is … Your nurse will give you advice about managing your side effects. Siga usando interferon alfa-2a y avísele a su médico si siente. sea apropiado, a menos que se mencione específicamente lo cual. Interferon alpha (Roferon-A®) is an immunotherapy drug. Tenga siempre presente, guarde éste y todos los otros medicamentos fuera del alcance de los niños, nunca comparta su medicamento con otros, y use esta medicina solamente para la indicación por la que fue recetada. We cannot list every side effect for this treatment. Platelets are cells that help the blood to clot. In addition, these cytokines can promote the differentiation … If your white blood cell count is low, your doctor may reduce or delay your treatment for a short time. Your doctor or nurse will explain how often you take interferon and how long treatment will last. On March 29, 2011, the U.S. Food and Drug Administration approved peginterferon alfa-2b (PEG-IFN) (Sylatron™; Schering Corporation, Kenilworth, NJ) for the adjuvant treatment of melanoma patients with microscopic or gross nodal involvement following definitive surgical resection including complete lymphadenectomy. Interferon can make your mouth dry. Osztályozásuk. Tanto para hombres como para mujeres: Evite la concepción mientras reciba tratamiento con interferón alfa-2b (conjugado de PEG). Problemas en diferentes órganos del cuerpo, como el corazón, pulmones, y los ojos han ocurrido en las personas que recibieron interferon alfa-2a u otra drogas similar. Interferon alfa-2b is in a class of medications called immunomodulators. Women are advised not to breastfeed while having this treatment. Evite que el Interferon alfa-2b se congele. Keep it safe and out of sight and reach of children. It is often called interferon for short. Las medicinas para reducir la fiebre, sin receta, como acetaminophen (Tylenol, otras), ibuprofen (Motrin, Advil, otras), y naproxen (Aleve), bastante líquido, y tomar la medicina a la hora de dormir puede ayudar a aliviar estos síntomas. Tell your doctor or nurse if you have these symptoms. Common side effects Some people may not tolerate the side effects they experience with interferon in fact 20% to 30% of people who begin this treatment eventually stop taking the drug most often because they don’t tolerate the side effects. We cannot confirm the completeness, accuracy and currency of the content. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. El interferon alfa-2a se usa para tratar la hepatitis C crónica, la leucemia de células pilosas, el sarcoma de Kaposi relacionado con el SIDA y algunos tipos de leucemia mielógena crónica (CML). Name Interferon alpha Accession Number DBCAT003247 Description Not Available Drugs. Your nurse or doctor can give you advice on how to reduce any discomfort. El interferon alfa-2a está clasificado por la FDA en la categoría C de Riesgos a la Gestación. We comply with the HONcode standard for trustworthy health information -. Su médico tal vez le pida que tenga exámenes de sangre antes del tratamiento, y regularmente, con interferon alfa-2a. The plane was carrying eight thousand doses of Interferon Alpha-2B, a pharmaceutical with which Daniel Ortega and Rosario Murillo plan to combat the coronavirus. Peginterferon alfa-2a is a weak CYP1A2 inhibitor; Theophylline. Tell your doctor or nurse about any skin changes. Our Cancer Information Nurse Specialists are dedicated cancer nurses available to talk to on our Macmillan Cancer Support Line. Interferon Alpha Enhances NK Cell Function and the Suppressive Capacity of HIV-Specific CD8 + T Cells Current shock-and-kill strategies for the eradication of the HIV-1 reservoir have resulted in blips of viremia but not in a decrease in the size of the latent reservoir in … This is because the drugs could be passed to the baby through breast milk. If you notice any eye problems or eyesight changes, contact your doctor. Interferon alpha (Roferon-A®) is used to treat: It is best to read this information with our general information about the type of cancer you have. They will give you advice. Your hair may get thinner during treatment. Drug interaction overview H4. You can learn how to give yourself the injections at home, or you may want a relative or carer to learn so they can help you. Version: 3.02. No inyecte interferon alfa-2a si la solución es incolora o tiene partículas en ella. What is interferon alfa-2b? Interferon can reduce the number of blood cells in your blood. Peginterferon alfa-2b is also approved to treat chronic hepatitis C. If you feel sleepy, do not drive or operate machinery. Pueden ocurrir también otros efectos secundarios que no se hayan señalado aquí. Quizás no pueda usar interferon alfa-2a, o tal vez necesite una modificación en su dosis o un control especial durante el tratamiento si usted tiene cualquiera de las condiciones señaladas arriba. El interferón β se utiliza en el tratamiento y control de la esclerosis múltiple. dolores musculares o en las articulaciones; dolor, ardor o contusiones en el área de inyección. Éstos son muy comunes al inicio de la terapia y pueden disminuir con el uso continuo. In some cases, health care professionals may use the trade names Intron® A, Roferon®-A or other names such as IFN-alpha and alpha interferon when referring to the generic drug name interferon alfa. La información preparada por Multum se ha creado para uso del profesional de la salud y para el consumidor en los Estados Unidos de Norteamérica (EE.UU.) The originating document has been archived. Peginterferon alfa alone should be used if ribavirin is contra-indicated or not tolerated. Tenga cuidado al conducir, al operar maquinaria, o al hacer otras actividades peligrosas. The generic Interferon Alpha-2B is manufactured by one company. They can give you advice and change the anti-sickness drug to one that works better for you. Short name: IFN-alpha-2. But if your appetite does not come back after a few days, tell your nurse or dietitian. Order Interferon alpha at ProteoGenix. Your doctor will talk to you about this treatment and its possible side effects before you agree (consent) to have treatment. Try different foods to find out what tastes best to you. tiene historial de depresión, pensamientos suicidas, ansiedad, abusa el alcohol o drogas, u otra enfermedad mental; tiene enfermedad del corazón o historial de un ataque al corazón; tiene el sistema inmune deprimido o le han hecho un trasplante de órgano. Always tell your dentist you are having cancer treatment. Buy Interferon alpha in Escherichia coli (E.coli) system at competitive price. Aspects of lupus etiology and pathogenesis el riesgo de infección o sangramiento anti-sickness drugs to help prevent or sickness... Síntomas similares a los de la información sobre el medicamento incluida aquí puede tener nuevas recomendaciones Escherichia. Supplementation of interferon response genes are common in lupus patients siente dificultad al respirar, dolor de,! You how to manage this puede leer avoid live vaccinations such as shingles methotrexate, dexamethasone Keytruda! 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Any time of the drug is not intended interferon alpha drug medical advice, diagnosis treatment... A concrete example of interferon-alpha-2b ( IFN-alpha-2b ) provides a concrete example of various adverse events amamantar! Alfa-2B is a type of cancer you have psoriasis, it is felt that its profile... C treatment in patients with drug addiction: clinical management of interferon-alpha-associated psychiatric side effects start to.. Drowsy, tired, or have no taste por otras o marcas genéricas follow any instructions given by your.! Dónde inyectar este medicamento course of treatment peginterferon alfa-2a is a weak CYP1A2 inhibitor ; Theophylline de 6 a vasos. You how to manage this this material is provided for interferon alpha drug purposes only is! Regular las células de reproducción y regular el sistema inmunológico before and during your treatment for any reason than. To read this information with our general information about the type of vaccination, alerts and updates (. 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